Senior Research Associate, Purification/Analytical Chemistry

Senior Research Associate, Purification/Analytical Chemistry

W2 Contract

Salary Range: $104,000 - $124,800 per year

Location: South San Francisco, CA - Onsite Role

Job Summary:

The ideal candidate will have experience in purifying macrocyclic peptides and/or small molecules, as well as strong expertise in liquid chromatography, mass spectrometry, and automated liquid handling systems. A proven track record of productivity and project ownership, along with a solid understanding of small molecules and peptide purification and analysis techniques, is essential.

Duties and Responsibilities:

• Perform semi-to-large-scale purification of macrocyclic peptides and/or small molecules on mg to gram using preparative LC/MS and analytical UPLC/MS.
• Optimize and support high-throughput purification workflows using prep-LC/MS and analytical LC/MS platforms, with some method development.
• Prepare samples using automated liquid handling systems.
• Deliver purified compounds to Compound Management team in either solid or liquid form, as determined by program needs.
• Represent the Purification/Analytical Chemistry team by sharing data and results with internal and external stakeholders as needed.
• Maintain accurate and timely documentation of lab activities; analyze data, generate reports, and communicate findings to cross-functional teams.
• Assist in drafting and revising protocols, methods, and Standard Operating Procedures (SOPs) under guidance. Manage ordering of chemicals and consumables; perform routine maintenance, troubleshooting, and coordination of service for lab instruments.
• Support broader lab activities such as synthesis, compound inventory management, and compound dispensing as needed.

Requirements and Qualifications:

• BA degree, at minimum, in Analytical Chemistry, Chemistry, Biochemistry, or a related scientific discipline. A Master's Degree is a plus.
• 8+ years of analytical chemistry experience
• Proven experience in operating, maintaining, and troubleshooting LC/MS and preparative LC/MS systems, including method development and data analysis.
• Hands-on experience with Waters SFC/MS, ACQUITY UPLC, QDa Mass Detector, Prep Auto Purification LC/MS System, Empower, MassLynx, Sirius miniTasker, GeneVac, and/or Lyophilizer preferred.
• Familiarity with structure elucidation using mass spectrometry is a plus.
• A background in organic synthesis and/or solid-phase peptide chemistry is a plus.
• Highly organized and detail-oriented, with strong data documentation skills and the ability to accurately follow written protocols and verbal instructions.
• Strong interpersonal skills and a collaborative mindset; able to thrive in a team-oriented environment.
• Must be able and willing to work at lab bench/fume hood for the majority of the workday
• Bachelor's degree required with 3 years of relevant experience in contracts administrative role (procurement, contract management, or purchasing departments) pharmaceuticals or biopharma industry.
• Track record of being a collaborative team player and business partner, building positive partnerships and adaptive to meet the needs of a growing business.
• Strong critical thinker and problem solver with a proactive mindset to build and manage processes and systems that drive accountability and results.
• Demonstrated ability to influence management and key business partners without authority.
• Excellent organizational skills, ability to multi-task, and prioritize effectively to deliver results within reasonably established timelines.
• Strong interpersonal skills, including verbal and written communication; able to represent and embody our corporate values.
• Proficient in Powerpoint, Excel, Word, and variety of project management (ie, smartsheets) and communication and administrative platforms (ie, Teams, contracts management system, etc).

Bayside Solutions, Inc. is not able to sponsor any candidates at this time. Additionally, candidates for this position must qualify as a W2 candidate.

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